THE EFFECT OF METFORMIN ON THE PROLIFERATION, APOPTOSIS AND CD133 MRNA EXPRESSION OF COLON CANCER STEM CELLS BY UPREGULATION OF MIR 342-3P

The Effect of Metformin on the Proliferation, Apoptosis and CD133 mRNA Expression of Colon Cancer Stem Cells by Upregulation of miR 342-3p

Yaqin Zhang, 1,* Ruofei Chen, 1,* Lili Deng, 2 Zongwen Shuai, 1 Mingwei Chen 2 1Department of Rheumatology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230022, People’s Republic of China; 2Department of Endocrinology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230022, People’s R

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Molecular epidemiology of Hepatitis delta virus infection in Minas Gerais state from Brazil, an area outside the hyperendemic region of the Amazon Basin

BACKGROUND Hepatitis delta virus (HDV) infections in hepatitis B virus (HBV) carriers are the most severe form of viral hepatitis.HDV prevalence is high in the Brazilian Amazon, but studies in other regions of the country are still scarce and often underestimated its prevalence by including a small numbers of individuals.OBJECTIVE This study aimed

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A Comparative Analysis of Genetic Diversity and Structure in Jaguars (Panthera onca), Pumas (Puma concolor), and Ocelots (Leopardus pardalis) in Fragmented Landscapes of a Critical Mesoamerican Linkage Zone.

With increasing anthropogenic impact and landscape change, terrestrial carnivore populations are becoming more fragmented.Thus, it is crucial to genetically monitor wild carnivores and quantify changes in genetic diversity and 5 Piece Twin Bedroom gene flow in response to these threats.This study combined the use of scat detector dogs and molecular

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